Today Apple has released Mac OS X 10.11.5. There is no know issues under this update for Hackintoshes. The update can be downloaded here.
X79 users will have to install the patched AICPM.Kext found on the x79 DMG (As needed) and patch AppleGraphicsDevicePolicy.Kext (under Mac-F60DEB81FF30ACF6 set Config1 to None). Boot with: nv_disable=1 to boot into the system prior to patching the driver.
Nvidia GPU users who need the Nvidia Retail Drivers boot with: nv_disable=1 and download the latest release here.
Last everyone will need to re-patch AppleHDA for onboard audio.